A comparative study established bromfenac as the best tolerated and more effective therapy than diclofenac and nepafenac in reducing cystoid macular edema (CME) after phacoemulsification.
The observational study included 243 patients receiving prophylaxis for the cystoid macular edema. The effectiveness of the treatment was evaluated using the pre-surgery and post-surgery assessments.
Bromfenac caused least ocular discomfort and showed highest medication adherence compared to nepafenac and diclofenac.
Bromfenac was more effective in reducing foveal volume compared to diclofenac and the nepafenac group.
Adapted from Capote AMC, Soto ML, Ruiz FR, Peláez EC, Vazquez AG, Suárez AR et. al. Comparative study of the efficacy and safety of bromfenac, nepafenac and diclofenac sodium for the prevention of cystoid macular edema after phacoemulsification. Int J Ophthalmol. 2018;11(7):1210-1216.
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