PURPOSE: To quantify the effectiveness of MiSight daily disposable soft contact lens in slowing the progression of juvenile-onset myopia.
Myopic children (spherical equivalent refraction, -0.75 to -4.00 D; astigmatism, <1.00 D) aged 8 to 12 years with no prior contact lens experience were enrolled in a 3-year, double-masked, randomized to receive either a MiSight 1-day contact lens (test) or Proclear 1-day (control; omafilcon A) and worn on a daily disposable basis.
Primary outcome: the change in cycloplegic spherical equivalent refraction and axial length
Of the subjects enrolled, 75.5% (109/144) completed the clinical trial (53 test, 56 control). Unadjusted change in spherical equivalent refraction was -0.73 D (59%) less in the test group than in the control group (-0.51 ± 0.64 vs. -1.24 ± 0.61 D, P < .001). Mean change in axial length was 0.32 mm (52%) less in the test group than in the control group (0.30 ± 0.27 vs. 0.62 ± 0.30 mm, P < .001). Changes in spherical equivalent refraction and axial length were highly correlated (r = -0.90, P < .001).
CONCLUSIONS: Results of this clinical trial demonstrate the effectiveness of the MiSight daily disposable soft contact lens in slowing change in spherical equivalent refraction and axial length
Reference: Optom Vis Sci 2019 Jul 19;[EPub Ahead of Print], P Chamberlain, SC Peixoto-de-Matos, NS Logan, C Ngo, D Jones, G Young
TAKE HOME MESSAGE
This prospective study demonstrates reduction in the rate of myopia progression over a period of 3 years in a cohort of children aged 8 to 12 years who wore daily disposable contact lenses with dual focus versus a control group of children wearing standard single-vision daily disposable lenses for myopia correction.
There was a correlated reduction in axial elongation among children wearing the dual-focus design lens.
Both the study and control groups were successful with soft contact lens wear.